Side Effects
Constipation on GLP-1 Medications:
Causes and Solutions
Reduced bowel frequency and difficulty with bowel movements.
How common is constipation?
Approximately 24 out of 100 people taking GLP-1 medications report experiencing constipation.
What causes constipation
Delayed gastric emptying and slowed GI motility
Reduced food volume and fiber intake
Dehydration
Reduced physical activity
Evidence-based solutions
Increase fiber intake gradually (25–35g/day)
Drink adequate water throughout the day
Stay physically active — walking helps motility
Consider magnesium citrate supplement
When to talk to a provider
While constipation is common among GLP-1 users, you should contact your healthcare provider if you experience any of the following:
- Symptoms are severe or worsening despite following the solutions above
- The symptom persists for more than 2–3 weeks after a dose change
- It significantly impacts your daily activities or quality of life
- You notice any new or unexpected symptoms alongside constipation
- You're considering stopping your medication due to the side effects
Your provider may adjust your dose, recommend specific supplements, or suggest alternative approaches. Never stop or modify your GLP-1 medication without medical guidance.
Concerned about constipation on GLP-1?
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